Rational use of drugs wikipedia. 49 pages, ref no SEA/Drugs/83 Rev.

Rational use of drugs wikipedia 2) Irrational drug use can occur when patients do not receive the proper drug, dose, duration or when higher cost drugs are used unnecessarily. Rational use of medicines requires that “patients receive The Government of India, through the National Health Policy (2017), emphasizes the importance of rational use of medicines, including pharmacovigilance, in healthcare settings. 1 It encompasses rational prescribing (good diagnosis practice and good prescribing practice, ie, the process of safe, effective, and economical ordering of drugs for the benefit of the Phadke A. Drug supply and use: towards a rational drug policy in India. In this sense it is more useful for modeling some everyday situations than a monotone consequence relation because the latter relation models facts in a more strict boolean fashion—something either follows under all circumstances or Jan 1, 2018 · Later in 1985, the Conference of Experts on the Rational Use of Drugs, convened by the World Health Organization (2002b), defined rational medicine use as “The rational use of drugs requires that patients receive medicines appropriate to their clinical needs, in doses that meet their own individual requirements, for an adequate period of time AH25086 was the second compound developed and showed a vasoconstriction effect but was not released as a drug due to low per oral bioavailability. McKenna's meetings with "entities from other dimensions" led him to believe in ideas like collective consciousness and consciousness being the fundamental substance of May 9, 2009 · The following 16 pages use this file: File:20drugs. ” WHO Definition “Patient receiving medication appropriate to their clinical needs, in appropriate doses National Essential Drug Policy including Rational Use of Medicines Irrational use of medicines is a serious public health crisis that is causing considerable harm to patients in terms of poor patient outcomes, impoverishment (through large and unnecessary expenditure), unnecessary side-effects, antimicrobial resistance, morbidity and death. 005 September 2002. 1159/000362803. These include. A Conference of Experts on the Rational Use of Drugs, convened by the World Health Organization in Nairobi in 1985 defined that: “Rational use of drugs requires that patients receive medications appropriate to their clinical needs, in doses that meet their own individual requirements for an adequate period of time, and the lowest cost to them Rational Use of Drugs (INRUD) coordinated by Management Sciences for Health, USA. 2%). svg; File:Rational scale to assess the harm of drugs (mean physical harm and mean dependence)-ru. Street, Parel, Mumbai 400 012, Maharashtra, India. 1. 184. 7%), essential medicine list (n = 586, 86. The essential medicine list (EML), accessibility, affordability and availability of EM have been some of the important issues in RUM. - Free download as Powerpoint Presentation (. It Rational drug use is defined as the process of appropriate prescribing, and dispensing of drugs for the appropriate patient for diagnosis, prevention, and treatment of diseases. When the basic principle of rational use of drugs is not fulfill it leads to irrationality which further leads to adverse effects and toxicity. This course teaches the investigation of medicine use in primary health care and how to promote rational use of medicines by providers. 5 It is commonly expressed in terms of polypharmacy, inappropriate use of antimicrobials, over-use of injection, failure to prescribe in accordance with clinical guidelines, and inappropriate self-medication File:Rational scale to assess the harm of drugs (mean physical harm and mean dependence). Jan 6, 2025 · Terence Kemp McKenna (1946–2000) was an American 'psychonaut', ethnobotanist, metaphysical philosopher, and advocate for the informed use of entheogenic psychedelics — known for his lectures and theories on such topics. "Development of a rational scale to assess the harm of drugs of potential misuse" The Lancet 2007; 369:1047-1053. png; File:Development of a rational scale to assess the harm of drugs of potential misuse (physical harm and dependence, NA free means). There is 3 M concept in Rational Use of Medicines (RUM): Medicines Mean Money. No description defined. WHO Technical Report Series 825. Keywords: WHO, Rational drug use. . Working towards rational use of medicines A major step towards rational use of medicines was taken in 1977, when WHO established the 1st Model Affiliation 1 National Chair Clinical Pharmacology (ICMR), National Institute for Research in Reproductive Health, J. svg 380 × 380; 7 KB Essential Drugs Monitor - periodical issued twice a year, covering drug policy, research, rational drug use and recent publications. 67±0. WHO Action Programme on Essential Drugs in the South-East Asia Region - report on an Intercountry Consultative Meeting, New Delhi, 4–8 March 1991. Sep 14, 2016 · It contains summary information on a selected number of drugs usually based on essential drug list, provide information about the drug’s generic name, strength, dose, route of administration and dosage. The drug control authority, the teaching institutes, drug industries, HC providers & the patient himself are helpful for rational drug use. svg Jul 25, 2023 · The following 5 pages use this file: File:20drugs. A sound rational drug use programme in any country has three elements: Rational use of medicines strategy and monitoring -- advocating rational medicines use, identifying and promoting successful strategies, and securing responsible medicines promotion. Rational use of antidepressant drugs Psychother Psychosom. Psychedelics are a subset of hallucinogenic drugs along with dissociatives (which produce feelings of detachment, e. svg Oct 1, 2023 · English: Radar plot depicting the data presented in Nutt, David, Leslie A King, William Saulsbury, Colin Blakemore. 2%, a significantly lower percentage than these of studies in United Kingdom (90%), 26 Namibia (80%), 27 Hong Kong (78. The base work this work was based on is in the public domain. Indian market's fixation with fixed dose combinations (Editorial) Rational Drug Bulletin. Odegova, PhD, ScD Perm State Pharmaceutical Academy, Perm, Russian Federation _____ Abstract In this article, the problems encountered in the rational use of drugs are discussed, one of the Rational use of medicines A pharmacist is one of the inevitable members of healthcare team who can help in achieving the goal of rational use of drugs. Three tools have been identified to implement Rational Use of Medicines effectively. Continued research led to the discovery of the first triptan drug, sumatriptan, that had both vasoconstriction effect, as well as better oral bioavailability. The rational use of drugs was defined as prescribing an effective drug for the patient (85. 9%), and prescribing a safe drug for the patient (77. So has the utilization of these facilities by the The following 16 pages use this file: File:20drugs. The canonical theory comes from work done by Kevin M. Apr 27, 2024 · The War on Drugs is a misbegotten attempt to "purify" American youth (and adults) by putting anyone caught with any quantity of illegal drugs in jail for a long time. Thus, RUM means less profit and income for those dealing with medicines; prescribers, and sellers. Working towards rational use of medicines A major step towards rational use of medicines was taken in 1977, when WHO established the 1st Model. On the contrary, irrational or non-rational use is the use of medicines in a way that is not compliant with rational use as defined above. svg; File:Rational scale to assess the harm of drugs (mean physical harm and mean dependence). Amitava S. Sep 21, 2021 · In our research, the prevalence of respondents having rational behavior of antibiotics use was 51. A commonly assumed pattern is that alcohol or nicotine use will lead to marijuana use, followed by cocaine, methamphetamine, or heroin use, in a manner similar to a slippery slope. May 19, 2015 · 8. Language Label Description Also known as; English: The EDM provides "global guidance on essential drugs and medicines, and working with countries – at their request – to implement national drug policies to ensure equity of access to essential drugs, drug quality and safety, and rational use of drugs. View Show abstract Apart from the interdisciplinary focus and emphasis on understanding behavioural aspects of medicines use, key principles are that The International Network for Rational Use of Drugs encourages rational use of medicines in low and middle income countries with both the promotion of well-designed research studies to understand these behavioural Rational Use of Drugs Ppt. Valuable inputs were made by the following individuals who, in addition to contributing to the background papers, assisted in reviewing Mar 16, 2018 · The rational use of medication receives little attention in the US from a national perspective, but it is becoming more important as health care costs continue to soar, affecting economic growth in this country and as the US debates health care reform. Apr 7, 2018 · 3. It defines rational use as patients receiving medicines appropriate for their clinical needs in doses that meet individual requirements, for adequate time periods, and at lowest cost. Available on the website Promoting Rational Drug Use. He wrote a series of books, starting with The Teachings of Don Juan, in which he purports to describe the teachings of "Don Juan Matus", a Yaqui Native American from Mexico and a traditional nagual, a shape-shifting magician. Essential Medicines List; Standard Treatment Guidelines and ; Drug Formulary Page 2: WHO Policy Perspectives on Medicines — Promoting rational use of medicines: core components implement interventions to promote more rational use of medicines (Box 2). svg Sep 22, 2020 · The following 16 pages use this file: File:20drugs. g. 4 Relatively similar percentage was detected in one of previous studies with 55% of respondents in Spain Jul 24, 2024 · Cocaine is a hell of a[1] drug refined from the coca plant specifically Erythroxylum coca var. Drug design, often referred to as rational drug design or simply rational design, is the inventive process of finding new medications based on the knowledge of a biological target. Sep 30, 2023 · "Development of a rational scale to assess the harm of drugs of potential misuse" The Lancet 2007; 369:1047-1053. edit. For more information, see image. [accessed on October 9, 2015]. The lists serve as a baseline for health insurance entities to include or exclude the medication, and modify the dose based on clinical study evidence. svg; File:Rational scale to assess the harm of drugs (mean physical harm and mean dependence) zh hans. Sep 14, 2024 · Drugs are natural or synthetic chemicals that affect biochemical processes in living organisms. In its refined form, it presents as a white powder at one end of a rolled-up hundred dollar bill, of which the other end is inserted in one's nostril. Another variation posits that some dealers will spike their supplies of marijuana Aug 28, 2023 · File:Rational scale to assess the harm of drugs (mean physical harm and mean dependence) tr. As shocking as it may seem to stick a $100 bill up one's nose, if you've reached the point where you're doing cocaine, you've probably It is, however, regulated by the Food and Drug Administration under the Food Drug and Cosmetics Act. [Google Scholar] 4. coca. 73% (± 27. Promoting rational use of medicines: core components-WHO policy perspectives on medicine no. It considers some of the factors underlying irrational medicine use and possible strate-gies to address the problem. 49 pages, ref no SEA/Drugs/83 Rev. Page 2: WHO Policy Perspectives on Medicines — Promoting rational use of medicines: core components implement interventions to promote more rational use of medicines (Box 2). Mar 24, 2024 · Project MKULTRA (or MK-ULTRA) was a secret CIA program to research mind control and chemical weapons/interrogation tools via the use of drugs such as amphetamine, MDMA, morphine, bufotenin, scopolamine, marijuana, salvia divinorum, alcohol, psilocybin, sodium pentothal, ergine, Bromo-DragonFLY,[1] bulbocapnine,[2] and most famously LSD. Promoting Rational Drug Use course in English, Spanish, and French (WHO, 2010). Add languages. DTC formulates policies and guidelines for the rational use of drugs and other pharmaceutical products. Drugs subject to abuse . Feb 11, 2009 · The document discusses the relationship between the amount of drug in the body and its effect, known as the dose-effect relationship. Sumatriptan was first launched in the English: A rational scale to assess the harm of drugs. Rational use of antidepressant drugs. 98 items per prescription. M. In the field of drug discovery, classical pharmacology, [1] also known as forward pharmacology, [2] [3] [4] or phenotypic drug discovery (PDD), [5] relies on phenotypic screening (screening in intact cells or whole organisms) of chemical libraries of synthetic small molecules, natural products or extracts to identify The strategy behind rational drug design is to develop a new drug that is capable of affecting a specific biological target, or in this case a special neural site of action (uptake pumps, receptors), while trying to avoid effects on other site of actions. 2014;83(4):197-204. doi: 10. [Google Scholar] 6. [3] Started in 1953 by then CIA Promotion of Rational Use of Drugs, and UNESCO Chair in Regional Use of Drugs, Chulalongkorn University, Bangkok in preparing the first draft and contributing to its subsequent development are deeply appreciated. svg (original) Licensing. As hypnotics, benzodiazepines are mainly indicated for transient or short term insomnia, for which prescriptions should if possible be limited to a few days Jan 15, 2021 · The TB programs need to give emphasis on the effective and rational use of second line drugs for newly diagnosed MDR-TB patients to prevent the emergence of pre-XDR/XDR-TB strains. svg Oct 1, 2021 · Definition Rational Use of Drugs : • The World Health Organization has defined Rational Use of Drugs as follows: • “The rational use of drugs requires that patients receive medicines appropriate to their clinical needs, in doses that meet their own individual requirements, for an adequate period of time, and at the lowest cost to them and Rational Drug Use Patient & community Prescriber, dispenser& their work Places Policy, Legal and Regulatory framework Drug Supply System. By the beginning of the 21st Century, Sri Lanka had approximately 9,000 registered medicinal drugs, hundreds of which were non-essential, unnecessary, highly expensive or even dangerous. Oct 3, 2014 · English: A rational scale to assess the harm of drugs. Essential Medicine List Concept and Rational Use of Medicine For BNS 1st Year Dr. The Rational Use of Drugs by World Health Organization (WHO), January 1987, World Health Organization edition, Hardcover in English Dec 10, 2023 · Carlos César Salvador Arana Castañeda (1925–1998) was a popular author and hoaxer influential in the psychedelic drug culture of the 1960s and 1970s. svg; File:Rational harm assessment of drugs radar plot. ketamine) and deliriants (which produce a state of confusion, e. Atropa belladonna). PMID:17382831. txt) or view presentation slides online. Rational Use of Drugs (Q93841391) From Wikidata. The basic principle for the rational use of drug is better supply of drugs, better prescribing and lower costs for health care2. Forward (classical) and reverse pharmacology approaches in drug discovery. [1] Notable psychedelic substances include: Feb 17, 2020 · Rational Use of Drugs WHO Definition The rational use of drugs requires that patients receive medications appropriate to their clinical needs, in doses that meet their own individual requirements for an adequate period of time, and at the and at the lowest cost to them and their community. One of its armaments is setting mandatory sentences for "crack" cocaine possession at roughly 18 times the length of sentences for possession of "powder" cocaine. [13] OTC Bayer medication with child-resistant packaging (cap) and tamper-resistant carton and innerseal Photo of the packaging of four medicines dispensed in the United Kingdom showing their Product Licence Numbers and symbols denoting if they are Prescription Only Medicine (POM) or Pharmacy Medicine (P), or lacking either, denoting General Sales List (GSL). name of drugs with dosage forms, dosage This document discusses rational use of medicines. Assessing the problem of irrational use. Pravin Prasad 1st Year Resident, MD Clinical Pharmacology Institute of Medicine, Maharajgunj, Kathmandu 1st December, 2015 (Mangsir 14, 2072), Tuesday General Pharmacology May 20, 2022 · Rational drug use implies correct drug, appropriate indication and selection with respect to efficacy, safety, suitability for the patient and cost. It has been digitally Aug 8, 2022 · What is rational use of drugs? The rational use of drugs requires that patients receive medicines appropriate to their clinical needs, in doses that meet their own individual requirements, for an adequate period of time, and at the lowest cost to them and the community (WHO 1985) Mar 22, 2022 · Prescriptions were dispensed for 52. svg Mar 1, 2024 · Chippers may, for example, smoke pot on a daily basis, but use "harder" drugs less often enough that they don't become addicts. RATIONAL PRESCRIBING. [Google Scholar] 3. New Delhi: Sage Publications; 1998. 2002;12:1. Medicines play… Nov 27, 2013 · The document discusses the rational use of drugs and outlines several key points: 1) Rational drug use means prescribing the appropriate medication based on a patient's clinical needs at the lowest cost. principle of rational use of medicines, and include adherence by patients; Concerned that insufficient attention and resources are being directed towards tackling the problem of irrational use of medicines by prescribers, dispensers and consumers; This chapter defines rational medicine use and gives examples of irrational medicine use and the adverse effects that can result. Murphy and Gary Becker . Rational_scale_to_assess_the_harm_of_drugs for discusion. Jun 17, 2024 · The gateway drug theory unproven hypothesis is an assertion that the use of "softer" drugs will lead to the use of "harder" drugs. English: A rational scale to assess the harm of drugs. Recreational drug use is the use of one or more psychoactive drugs to induce an altered state of consciousness, Rational drug use is a fundamental concept in healthcare that aims to ensure the appropriate and effective use of medications for optimal patient outcomes. svg; File:Rational scale to assess the harm of drugs (mean physical harm and mean dependence)-es. World Health Organization. svg. 44) of the patients, with a mean of 2. They differ from food in that, unlike foodstuffs, drugs are not consumed for nutritional purposes, but rather for their physical and/or psychoactive effects (there is overlap; a food product may contain or be partially made up of one or more substances that is technically classified a drug, like Other Titles Uso racional de los medicamentos : informe de la Conferencia de Expertos, Nairobi, 25-29 de noviembre de 1985 L' usage rationnel des médicaments : rapport de la Conférence d' experts, Nairobi, 25-29 novembre 1985 The Rational Use of Drugs by World Health Organization (WHO), 1987, World Health Organization, WHO Publications Center USA [distributor] edition, in English Dec 25, 2015 · 1. Jul 1, 1994 · Rational use requires consideration of the large differences in potency and elimination rates between different benzodiazepines, as well as the requirements of individual patients. More than 600 people have already benefited from participating in this course which has been held in many Mar 18, 2024 · A psychedelic drug is one that induces a lucid altered state of consciousness. ppt / . DEFINITION Rational drug use can be defined as the usage of appropriate drug with proven safety & efficacy for the right patient in the appropriate dose and dosage form at proper intervals of time at low cost. It contains not only the physical harm and dependence data like the aforementioned image, but also the mean social harm of each drug. " Mar 30, 2024 · The following 16 pages use this file: File:20drugs. DSPUD was in The use of essential medicines lists has resulted in better quality of care and improved management of health resources in the most cost-effective manner. Mar 1, 2019 · Attitudes of 40 interns towards rational drug use (RDU) were assessed, using a standardized Likert type scale. Introduction Rational use of drugs is one of the old concept evolved as early as 300B. svg; File:Rational scale to assess the harm of drugs ko. The Use of Essential Drugs. svg 900 × 900; 3 KB Rational scale to assess the harm of drugs (mean physical harm and mean dependence) fa. Steps of rational drug use Step:- I Identify the patient’s problem based on symptoms & recognize the need for action Step:- II Diagnosis of the disease – define the diagnosis Step:- III List possible intervention or treatment (drug or no drug) – Identify the drug Step:- IV Start the treatment by writing an accurate & complete prescription e. C. WHO: The rational use of drugs requires that patient receive medication appropriate to their clinical needs, in doses that meet their own individual requirements for an adequate Jun 21, 2019 · Rational Use of Drugs Rational means “based on or in accordance with reason or logic” “Rational use of drug means the right drug for the right patient, in the right dose, at right time, by the right route and should be economical. Promoting the rational use of medicines will result in improved quality and increased accessibility of drugs leading to better quality of life for the community. File:Rational scale to assess the harm of drugs (mean physical harm and mean dependence) ja. Results: As early as 1994, seeds of rational use of medicines were sown in the country with two initiatives: establishment of a civil society, Delhi Society for Promoting Rational Use of Drugs (DSPURD) and establishment of government agency in Tamil Nadu, a southern state, called Tamil Medical Services Corporation Limited (TNMSCL). It is the largest supplier of drugs in the country, and is tasked with providing quality-assured health care items that are safe and effective, at an affordable price, while educating the public on the rational use of drugs. 1 Rational use of drugs requires that patients receive medications appropriate to their clinical needs, in doses that meet their own individual requirements, for an English: A rational scale to assess the harm of drugs. PNG; File:Rational scale to assess the harm of drugs (mean physical harm and mean dependence) zh. Scribd is the world's largest social reading and publishing site. A rational drug policy is one based on drug use in which patients receive medications appropriate to their clinical needs, in doses that meet their own individual requirements, for an adequate period of time, and at the lowest cost to them and their community. The number of doctors, nurses and paramedical staff in public facilities has increased markedly. [11] [12] Use of physical restraints such as straitjackets also declined. This presentation identifies factors contributing to irrational use at the international, national, health systems, prescriber, dispensing, and patient levels. The State Pharmaceuticals Corporation (SPC) is a state-owned enterprise with its headquarters in Colombo, Sri Lanka. Jump to navigation Jump to search. The use of essential drugs. "Development of a rational scale to assess the harm of drugs of potential misuse" The Lancet 2007; 369 In behavioral economics, rational addiction is the hypothesis that addictions can be usefully modeled as specific kinds of rational, forward-looking, optimal consumption plans. What links here; Related changes; Upload file; Special pages; Permanent link; Page information; Get shortened URL; Download QR code World Health Organization. pdf), Text File (. 1%) and could name parts of a prescription (n = 600, 88. Prosecution is possible under its "misbranding" clauses, prohibiting the sale or distribution of nitrous oxide for the purpose of human consumption (the recreational drug use market). 5 Interest in the rational use of medications comes from diverse directions, such as insurance companies, physician groups, politicians, and Mar 12, 2018 · This document discusses rational use of over-the-counter (OTC) medications. Rational use of medicines means that “patients receive medications appropriate to their clinical needs, in doses that meet their requirements, for an adequate period English: Radar plot depicting the data presented in Nutt, David, Leslie A King, William Saulsbury, Colin Blakemore. Page contents not supported in other languages. It provides examples of common OTC drug categories and explains that rational use means using the appropriate medication, in the proper dose, for the right duration and indication. The assessment was repeated after 4 months to evaluate the effect of usual working Rational harm assessment of drugs radar plot. Chippers may be at risk of becoming addicts. It explains that this relationship is determined by several factors in a causal chain, including the dose of the drug, the concentration of drug at the target site, the formation of drug-receptor complexes, and the response. • Promoting rational drug (medicine) use in the community, in collaboration with the University of Amsterdam, The Netherlands. 1%), Table 3. The following strategies have been advocated by WHO for promoting rational use of medicines. p. png; File:Rational scale to assess the harm of drugs (mean physical harm and mean dependence)-es. perceptions and economic conditions”. 5%) and Sydney (76. Given the necessity of proving the intent of either buyer or The concept of rational use of medicines (RUM) As defined by the World Health Organization (WHO), the rational use of medicines requires that “patients receive medications appropriate to their clinical needs, in doses that meet their own individual requirements, for an adequate period of time, and at the lowest cost to them The Drug Equality Alliance is a non-profit organisation based in the United Kingdom whose mission statement is: . 4%), prescribing an appropriate drug for the patient (84. Promoting Rational Drug Use: The Need for a National Rational Drug Use Sub-Mission Introduction: The Issues Health system strengthening is a central mandate of the National Rural Health Mission. The rational consequence relation is non-monotonic, and the relation is intended to carry the meaning theta usually implies phi or phi usually follows from theta. svg 31 CONCLUSION Irrational use of drugs not only waste resources, but also leads to drug induced disease. The issue of rational use of medicines (RUM) has been throbbing since decades and the essential medicine (EM) concept has been pulsating for almost a quarter century. As of 2013, the 10 most prescribed psychiatric drugs by number of prescriptions were alprazolam, sertraline, citalopram, fluoxetine, lorazepam, trazodone, escitalopram, duloxetine, bupropion XL, and venlafaxine XR. Strategies to Promote Rational Use of Medicines. The document outlines factors influencing medicine use including policy, prescribers, patients, and pharmaceutical supply systems. Data source is the March 24, 2007 article: Nutt, David, Leslie A King, William Saulsbury, Colin Blakemore. It is made to transform the "War on Some People who use Some Drugs" from its subjective historical and cultural roots into a rational and objective legal regulatory framework that secures equal rights and equal protection to all those who are concerned with dangerous or otherwise Drug Development and Rational Use of Drugs Rational Use of Drugs: Pharmaceutical Aspects of the Drug Selection Natalya B. [1] The drug is most commonly an organic small molecule that activates or inhibits the function of a biomolecule such as a protein , which in turn results in a Rational drug use (RDU) is the process of appropriate prescribing, dispensing, and patient use of drugs for diagnosis, prevention, and treatment of diseases. Aspects of irrational use In an ideal world no person should ever be arrested for possession of these drugs but society should encourage (with or without a stick) treatment for those drugs at the far ends of the scale and they should recognize the damage caused by presently legal drugs before ranting and lying about the affects of other drugs which are shown to cause The National Medicinal Drugs Policy is an essential part of Sri Lanka's Health Policy, aimed at the rational use of pharmaceuticals. "Development of a rational scale to assess the harm of drugs of potential misuse" The Lancet 2007; 369 On rational use of medicine, most participants reported awareness of the terms rational use of medicine (n = 631, 92. Jan 28, 2017 · Irrational use can occur when there is polypharmacy, unnecessary or incorrect medications, underuse of effective medicines, or unsafe drug use. In a broader way we can define rational use of drugs as, “prescribing right drug in adequate dose for the sufficient duration appropriate to the patients at lowest cost” The irrational use of drug is a serious Jan 1, 2019 · Similar committees could also work at public health (governmental and nongovernmental agencies) levels to develop state/national formularies and advice on the rational management of drugs in the region. png 1,000 × 1,000; 170 KB Rational harm assessment of drugs radar plot. Rostova, PhD, ScD*, Tatiana F. Geneva: World Health Organization; 1992. pptx), PDF File (. Encourage use of drug therapeutic committee (DTC); so as to increases the safe and effective use of medicine in the facility hence provide English: A rational scale to assess the harm of drugs. Virtually every drug can be abused, though some are much more harmful than others, and some are relatively harmless but extremely addictive.